Biography
Biography: Anurag Tripathi
Abstract
Objectives: Th e present study evaluated the level of salivary α-amylase (sAA) in healthy individuals and myofascial pain syndrome (MPS) patients and evaluated the reliability of salivary α amylase as a biomarker for pain.
Methods: Following ethical approval, the salivary sample for estimation of amylase was taken using Navazesh method of clinically diagnosed MPS patients (criteria by RDC) (group-1) and age and sex matched control group (group-2). Visual analog scale (VAS) score for each individual was recorded co-related with salivary amylase. Statistical analysis was done using SPSS
soft ware 16.0.
Results: Th e sAA was signifi cantly higher amongst group-1 (149.92±21.1) compared to group-2 (91.18±5.4). Th ere was signifi cant diff erence in VAS among diff erent age groups and sex. Th e salivary α amylase levels progressively reduced in patients as the age increased in group-1. However, mild negative correlation was found between VAS and sAA in group-2.
Conclusion: Th e study highlights the sensitivity of sAA as an eff ective marker in assessment of pain severity in MPS patients on the basis of VAS scale. Th e level of salivary α-amylase was signifi cantly correlated with the pain severity assessed by VAS.